Studies on the immunity of Newcastle disease virus

Studies on Newcastle Disease Virus

1. It is likely that certain tailed and filamentous particles seen on electron microscope examination of partially purified saline suspensions of Newcastle virus are the individual virus particles because: (a) They have a highly characteristic shape not seen in other virus preparations. (b) They are present whenever the virus is present in high concentration. (c) Their size agrees with the size...

Studies on the immunogenic properties of three lentogenic strains of newcastle disease virus

Studies on Newcastle disease virus by the plaque method.

The establishment of a successful plaque method for counting infectious virus particles by Dulbecco (1952), with subsequent refinements by Dulbecco and Vogt (1953, 1954a), makes it possible to quantitatively assay animal viruses with a high degree of accuracy in a manner comparable to assays of bacterial viruses. Two methods of assay commonly used in characterizing any particular Newcastle dise...

Herd immunity to Newcastle disease virus in poultry by vaccination

Newcastle disease is an economically important disease of poultry for which vaccination is applied as a preventive measure in many countries. Nevertheless, outbreaks have been reported in vaccinated populations. This suggests that either the vaccination coverage level is too low or that vaccination does not provide perfect immunity, allowing the virus to spread in partially vaccinated populatio...

Immunogenicity of the Multi-Epitopic Recombinant Glycoproteins of Newcastle Disease Virus: Implications for the Serodiagnosis Applications

Background: Newcastle disease virus (NDV) is a dangerous viral disease, infecting a broad range of birds, and has a fatal effect on the poultry industries. The attachment and consequently fusion of the virus to the host cell membrane is directed by the two superficial glycoproteins, the hemagglutinin-neuraminidase (HN) and the fusion (F) which is considered as the important tar...